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(2.2) To reduce the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death, increase the dosage to 1 mg once weekly after at least 4 weeks on the 0.5 mg dosage

The higher dose produced results comparable to tirzepatide, suggesting that dose intensity is a significant variable in GLP-1 agonist efficacy

The most commonly reported adverse effects of semaglutide are gastrointestinal in nature, affecting a substantial proportion of patients

In comparison, those on a placebo lost only 1.5% of their body weight and saw minimal changes in waist size

Semaglutide GLP-1 functions by imitating a natural hormone in your body that aids in controlling appetite and promoting a sense of fullness

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